diff --git a/GFramework.Core.Tests/Ioc/MicrosoftDiContainerTests.cs b/GFramework.Core.Tests/Ioc/MicrosoftDiContainerTests.cs
index 4e3b5b23..19c59dcb 100644
--- a/GFramework.Core.Tests/Ioc/MicrosoftDiContainerTests.cs
+++ b/GFramework.Core.Tests/Ioc/MicrosoftDiContainerTests.cs
@@ -401,6 +401,17 @@ public class MicrosoftDiContainerTests
             Is.True);
     }
 
+    /// <summary>
+    ///     测试当程序集集合中包含空元素时，CQRS handler 注册入口会在委托给注册服务前直接失败。
+    /// </summary>
+    [Test]
+    public void RegisterCqrsHandlersFromAssemblies_WithNullAssemblyItem_Should_ThrowArgumentNullException()
+    {
+        var assemblies = new Assembly[] { typeof(DeterministicOrderNotification).Assembly, null! };
+
+        Assert.Throws<ArgumentNullException>(() => _container.RegisterCqrsHandlersFromAssemblies(assemblies));
+    }
+
     /// <summary>
     ///     测试冻结容器以防止进一步注册的功能
     /// </summary>
diff --git a/GFramework.Core/Ioc/MicrosoftDiContainer.cs b/GFramework.Core/Ioc/MicrosoftDiContainer.cs
index 5c49621a..6152366f 100644
--- a/GFramework.Core/Ioc/MicrosoftDiContainer.cs
+++ b/GFramework.Core/Ioc/MicrosoftDiContainer.cs
@@ -399,16 +399,22 @@ public class MicrosoftDiContainer(IServiceCollection? serviceCollection = null)
     /// </summary>
     /// <param name="assemblies">要接入的程序集集合。</param>
     /// <exception cref="ArgumentNullException"><paramref name="assemblies" /> 为 <see langword="null" />。</exception>
+    /// <exception cref="ArgumentNullException"><paramref name="assemblies" /> 中存在 <see langword="null" /> 元素。</exception>
     /// <exception cref="InvalidOperationException">容器已冻结，无法继续注册 CQRS 处理器。</exception>
     public void RegisterCqrsHandlersFromAssemblies(IEnumerable<Assembly> assemblies)
     {
         ArgumentNullException.ThrowIfNull(assemblies);
+        var assemblyArray = assemblies.ToArray();
+        foreach (var assembly in assemblyArray)
+        {
+            ArgumentNullException.ThrowIfNull(assembly);
+        }
 
         _lock.EnterWriteLock();
         try
         {
             ThrowIfFrozen();
-            ResolveCqrsRegistrationService().RegisterHandlers(assemblies);
+            ResolveCqrsRegistrationService().RegisterHandlers(assemblyArray);
         }
         finally
         {